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Introduction
Argatroban, as a direct thrombin inhibitor, prolongs the clotting time. However, detection of clotting time is the base of routine fibrinogen assays, including Clauss method and derived method. The influences of argatroban on fibrinogen assays are still unclear.
Methods
Normal pooled plasma (NPP) from 20 healthy subjects was spiked with increasing argatroban concentrations (0‐3.2 μg/mL)...
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