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Objectives: This study aimed to evaluate a novel three‐dimensional ultrasound (US) guidance system for use in hepatic microwave ablation (MWA).
Methods: An in vitro assessment was performed in which users with different degrees of experience were evaluated for accuracy in targeting phantom lesions embedded in agar using US alone, or US in conjunction with the InVision™ System (IVS). An eight‐patient...
Background: Gallstones appear more frequently in patients with cirrhosis and open cholecystectomy in this patient population is associated with higher morbidity and mortality. The aim of the present study was to evaluate experience with laparoscopic cholecystectomy in patients with cirrhosis and to provide recommendations for management.
Methods: Retrospective review of laparoscopic cholecystectomy...
Background: Intraoperative blood loss during liver resection may be minimized by ablating the liver parenchyma using radiofrequency (RF) energy. However, it is difficult to estimate the depth of the avascular plane and more RF energy than necessary may be inadvertently used as a result of lack of feedback.
Methods: Laparoscopic liver resection was performed on a live porcine model to determine the...
Objectives: An aberrant right hepatic artery (aRHA) is the most frequently encountered vascular anomaly during pancreatoduodenectomy (PD). This study was performed to investigate the incidence of aRHA in a large series of PDs and to explore its relationship with complications and survival.
Methods: In a consecutive series of 790 PDs, aRHA could be identified or ruled out in 758 patients by reviewing...
Introduction: Gemcitabine, the current standard of care for pancreatic ductal adenocarcinoma (PDA), has a less than 10% partial response rate. Genexol‐PM, a modified form of paclitaxel, has been shown to have antitumour effects in clinical trials of metastatic breast and small‐lung‐cell carcinoma. The aim of the present study was to determine if Genexol would be a beneficial treatment for gemcitabine‐resistant...
Background: There has been an increasing role of advanced minimally invasive procedures in hepatopancreatobilliary (HPB) surgery. However, there are no set minimum laparoscopic case requirements.
Methods: A 14‐question electronic survey was sent to 82 worldwide HPB fellowship programme directors.
Results: Forty‐nine per cent (n = 40) of the programme directors responded. The programmes were predominantly...
Objectives: This report describes a survey undertaken with the aim of assessing the current status of available fellowships in hepatopancreatobiliary (HPB) surgery in order to identify steps to be taken to ensure the provision of successful training in this specialty.
Methods: An online survey was conducted among members of the International Hepato‐Pancreato‐Biliary Association (IHPBA) targeting...
Objectives: Obesity is a significant risk factor for many liver diseases, including hepatocellular carcinoma (HCC). Leptin has been identified as a central mediator of factors that regulate energy intake and expenditure, including appetite, metabolism and fat storage. The role of leptin in the initiation, development and progression of HCC remains poorly understood. The aims of this study were to...
Background: The best treatment options for walled‐off pancreatic necrosis (WOPN) are not well defined. A retrospective study of patients treated for WOPN with transgastric debridement and internal drainage was undertaken.
Methods: Patients with symptomatic non‐infected WOPN treated with open transgastric debridement and internal drainage were evaluated.
Results: In all, 51 patients underwent surgical...
Introduction: Selected patients with isolated breast cancer liver metastases (BCLM) may benefit from surgical management; however, indications remain unclear and the risks may outweigh the benefits in patients with a generally poor prognosis.
Methods: Between 1998 and 2006, 17 patients diagnosed with BCLM were considered for surgical management (<4 tumours, tumour <4 cm in diameter and no/stable...
Background: The aim of the present study was to analyse the outcome after hepatic resection for non‐colorectal, non‐neuroendocrine, non‐sarcomatous (NCNNNS) metastatic tumours and to identify the factors predicting survival.
Methods: All patients who underwent hepatic resection for NCNNNS metastatic tumours between September 1996 and June 2009 were included. Patients' demographics, clinical and...
Objectives: This study examines changes in the expression of growth factors following thermal ablation (TA) of selected colorectal cancer (CRC) liver metastases.
Methods: Using mice with established CRC liver metastases, two tumours in each animal were thermally ablated. Liver and tumour tissues were collected at various time‐points (days 0, 1, 2, 3, 5 and 7) following TA treatment from the ablation...
Background: The diagnosis and staging of hilar cholangiocarcinoma (HCCA) remain challenging despite recent advances in imaging. Little is known about the use of positron emission tomography/computed tomography (PET/CT) in HCCA.
Objectives: This study aimed to evaluate the additional value of FDG‐PET/CT and standardized uptake value (SUV) in patients with highly suspected HCCA.
Methods: Between...
Background: Lymph node (LN) metastases are a major negative prognostic factor for peri‐hilar cholangiocarcinoma (PCC). Prognostic significance of the extent of LN dissection, number of metastatic LN and the lymph node ratio (LNR) are still under debate.
Aims: The aims of the present study were to evaluate the prognostic value of the LN status, the total number of LNs evaluated and LNR in PCC.
Methods: ...
Background: Surgical treatment of chronic pancreatitis is indicated for intractable pain. Frey's procedure is an accepted treatment for this disease. The aim of the present study was to describe a single‐centre experience in the treatment of chronic pancreatitis using Frey's procedure.
Methods: A retrospective analysis of 73 patients who underwent a Frey's procedure between 1991 to 2007 and had...
Background: Hilar cholangiocarcinoma presents both diagnostic and therapeutic challenges. While establishing a diagnosis is important for patients considering aggressive treatment, a transperitoneal fine needle aspiration (FNA) may lead to seeding of the tumour. The aim of the present study was to determine whether patients who have undergone transperitoneal FNA of the primary tumour have a higher...
Background: Laparoscopic liver resection (LLR) is now considered a feasible alternative to open liver resection (OLR) in selected patients. Nevertheless studies comparing LLR and OLR are few and concerns remain about long‐term oncological equivalence. The present study compares outcomes with LLR vs. OLR using meta‐analytical methods.
Methods: Electronic literature searches were conducted to identify...
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