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Background: Activating point mutations of GNAS at codon 201 have been detected in approximately two thirds of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. Intraductal papillary neoplasms of the bile ducts (IPNBs) morphologically resemble pancreatic IPMNs. This study sought to assess the mutational status of GNAS at codon 201 in IPNBs.
Methods: Thirty‐four patients were included...
Background: Right hepatectomy (RH) is the most common type of major hepatectomy and can be achieved without portal triad clamping (PTC) in non‐cirrhotic liver. The present study reviews our standardized policy of performing RH without systematic PTC.
Methods: One hundred and eighty‐one consecutive RH were performed in non‐cirrhotic patients, with division of the right afferent and efferent blood...
Objectives: The aim of this prospective study was to investigate the implementation of an enhanced recovery after surgery (ERAS) programme following pancreaticoduodenectomy (PD).
Methods: Patients undergoing PD were managed according to an ERAS protocol. Outcome measures included postoperative mortality, morbidity, hospitalization and 30‐day readmission rate. Key protocol targets were: nasogastric...
Background: Accurate pre‐operative imaging in pancreatic cancer helps avoid unsuccessful surgical explorations and forewarns surgeons regarding aberrant anatomy. This review aimed to determine the role of current imaging modalities in the diagnosis and determination of resectability of pancreatic and peri‐ampullary adenocarcinomas.
Methods: A systematic search of the scientific literature was carried...
Background: The aim of this meta‐analysis was to analyse the outcomes of major pancreatic surgery among the elderly (≥75 and ≥80 years of age).
Methods: A systematic literature search was conducted using Embase, MEDLINE, Cochrane and PubMed databases on all studies published between January 1990 and April 2012 reporting peri‐operative outcomes after a pancreaticoduodenectomy (PD) among the elderly...
Objectives: There are few data in the literature regarding the ability of surgical trainees and surgeons to correctly interpret intraoperative cholangiograms (IOCs) during laparoscopic cholecystectomy (LC). The aim of this study was to determine the accuracy of surgeons' interpretations of IOCs.
Methods: Fifteen IOCs, depicting normal, variants of normal and abnormal anatomy, were sent electronically...
Background: Delayed haemorrhage (DH) is a life‐threatening complication of pancreatic resection (PR) and the mortality rate for DH is very high. However, the risk factors and prognostic factors associated with DH are rarely evaluated.
Methods: A pancreatic resection was performed on 457 patients. Delayed haemorrhage was defined as bleeding from the surgical site ≥5 days after PR. Risk factors for...
Background: Gallbladder torsion is a rare disease, predominantly affecting elderly women. It is an important differential in the acute surgical abdomen.
Methods: A total of 324 published case reports of torsion of the gallbladder were reviewed. Features in diagnostic imaging suggestive of torsion were reviewed and summarized.
Results: Gallbladder torsion is primarily a disease of elderly people;...
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