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Aims
Barrett's oesophagus with indefinite for dysplasia (BE‐IND) is a subjective diagnosis with a low interobserver agreement (IOA) among pathologists and uncertain clinical implications. This study aimed to assess the utility of p53 immunohistochemistry (p53‐IHC) in assessing BE‐IND specimens.
Methods and results
Archive endoscopic biopsies with a BE‐IND diagnosis from two academic centres were...
Aims
To evaluate the frequency, subcellular localization, and variability of CD30 expression in mycosis fungoides.
Methods
This retrospective multicenter study investigated 135 biopsy specimens of 95 patients with mycosis fungoides for CD30 expression and CD30 staining pattern in relation to histomorphologic criteria, eosinophils, and tumour stage. We used two different CD30 cutoffs: (i) any CD30...
Neoadjuvant chemotherapy (NACT) has become the standard of care for high‐risk breast cancer, including triple‐negative (TNBC) and HER2‐positive disease. As a result, handling and reporting of breast specimens post‐NACT is part of routine practice, and it is important for pathologists to recognise the changes in tumour cells, tumour‐associated stroma and background breast tissue induced by NACT. Familiarity...