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Humphrey P A (2012) Histopathology60,Histological variants of prostatic carcinoma and their significance
The vast majority of prostatic cancers are acinar adenocarcinomas. Histological variants of prostatic carcinoma have been variably defined. One approach is to consider two groups of variants. The first group comprises histological variants of acinar adenocarcinoma and the second group non‐acinar...
AimTo study prostate cancer zonal differences in TMPRSS2–ERG gene rearrangement.
Methods and resultsWe examined 136 well‐characterized dominant anterior prostatic tumours, including 61 transition zone (TZ) and 75 anterior peripheral zone (PZ) lesions, defined using strict anatomical considerations. TMPRSS2–ERGFISH and ERG protein immunohistochemistry were performed on tissue microarrays. FISH results,...
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