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Aims
The real‐world efficacy of sofosbuvir/velpatasvir treatment for patients with hepatitis C virus‐related decompensated cirrhosis is unclear. We aimed to identify factors that improve liver functional reserve after treatment.
Methods
This was a multicenter retrospective study of 12‐week sofosbuvir/velpatasvir treatment. A total of 48 patients with Child–Pugh (CP) class B or C were enrolled at...
Background & aims
Cell‐derived small extracellular vesicles (sEVs) participate in cell–cell communication via the transfer of molecular cargo including selectively enriched microRNAs (miRNAs). Utilizing advances in sEV isolation and characterization, this study investigates the impact of liver injury and dysfunction on the circulating EV‐miRNA profile.
Methods
High‐throughput screening of 799...