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Background
Currently, bismuth quadruple therapy (BQT) is indicated as a first‐line treatment for Helicobacter pylori eradication in areas with high dual metronidazole and clarithromycin resistance, with its use being limited by its low tolerability and significant cost. A novel regimen with high‐dose amoxicillin dual therapy (HDADT) has emerged as an alternative. The aim of this study was to compare...
Introduction
In Chile, more than 70% of adults are infected by Helicobacter pylori. Clarithromycin should not be used in any regimen if there is >15% resistance to this antibiotic, being greater than 26% in our population. In this scenario, the effectiveness of triple therapy (proton pump inhibitor [PPI], clarithromycin, amoxicillin) was only 63.8%.
Aim
To evaluate the eradication rate and safety...
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