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Background
The incidence and risk factors for the development of high‐grade dysplasia (HG‐D) and laryngeal squamous cell carcinoma (LSCC) were assessed in patients with laryngeal squamous cell papillomas (LSP).
Methods
Clinical data, human papillomaviruses (HPV) typing, HPV E6/E7 mRNA in situ hybridization, and sequencing of host genes in LSP biopsies of 163 patients were analyzed.
Results
Progression...
Background
Laryngeal sarcoma is rare. We performed a systematic review and individual patient analysis to evaluate the patterns of care, prognostic factors, and role of radiotherapy in laryngeal soft tissue sarcoma.
Methods
A systematic search on PubMed and Google scholar was done. An individual patient data analysis was done.
Results
Of the 300 cases of laryngeal sarcoma, 80% underwent surgery...
Background
High‐grade neuroendocrine carcinoma of the larynx (HG‐NECL) is rare and aggressive with limited data regarding response to systemic therapy. We evaluated clinicopathological features, therapeutic approaches, and outcomes in patients with laryngeal or hypopharyngeal HG‐NECL.
Methods
Data were retrospectively collected through 1997–2020. Median disease‐free (mDFS), progression‐free (mPFS),...
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