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The neurotransmitter serotonin plays an important role in modulating diverse behavioral traits. Mice lacking the serotonin 1A receptor (Htr1a) show elevated avoidance of novel open spaces, suggesting that it has a role in modulating anxiety behavior. Htr1a is a Gαi‐coupled G‐protein‐coupled receptor expressed on serotonin neurons (auto‐receptor), where it mediates negative feedback of serotonin neuron...
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