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The notochord is the distinctive characteristic of chordates; however, the knowledge of the complement of transcription factors governing the development of this structure is still incomplete. Here we present the expression patterns of seven transcription factor genes detected in the notochord of the ascidian Ciona intestinalis at various stages of embryonic development. Four of these transcription...
Mid‐tailbud Ciona intestinalis embryo expressing GFP driven by the notochord specific cis‐regulatory module associated with the transcription factor Brachyury (green notochord cells). Embryos are counterstained with phalloidin (red) and DAPI (blue) to highlight F‐actin and nuclei, respectively. From José‐Edwards et al., Developmental Dynamics 240:1793–1805, 2011.
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