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Background: PRDM1 is a transcriptional repressor that contributes to primordial germ cell (PGC) development. During early gastrulation, epiblast‐derived PRDM1 is thought to be restricted to a lineage‐segregated germ line in the allantois. However, given recent findings that PGCs overlap an allantoic progenitor pool that contributes widely to the fetal–umbilical interface, posterior PRDM1 may also...
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