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Prostate contours delineation on Magnetic Resonance (MR) images is a challenging and important task in medical imaging with applications of guiding biopsy, surgery and therapy. While a fully automated method is highly desired for this application, it can be a very difficult task due to the structure and surrounding tissues of the prostate gland. Traditional active contours‐based delineation algorithms...
Purpose: Investigation of trabecular bone strength and compaction is important for fracture risk prediction. At 1–2% compressive strain, trabecular bone undergoes strain softening, which may lead to numerical instabilities and mesh dependency in classical local damage‐plastic models. The aim of this work is to improve our continuum damage‐plastic model of bone by reducing the influence of finite element...
Complex flow patterns exist within the asymmetric branching airway network in the lungs. These flow patterns are known to become increasingly heterogeneous during disease as a result of various mechanisms such as bronchoconstriction or alterations in lung tissue compliance. Here, we present a coupled model of tissue deformation and network airflow enabling predictions of dynamic flow properties, including...
Given measurement difficulties, earlier modeling studies have often used some constant ratios to predict lumbar segmental kinematics from measurements of total lumbar kinematics. Recent imaging studies suggested distribution of lumbar kinematics across its vertebrae changes with trunk rotation, lumbar posture, and presence of load. An optimization‐based method is presented and validated in this study...
This article introduces a meshing technique focused on fast and real‐time simulation in a biomedical context. We describe in details our algorithm, which starts from a basic Octree regarding the constraints imposed by the simulation, and then, mixed‐element patterns are applied over transitions between coarse and fine regions. The use of surface patterns, also composed by mixed elements, allows us...
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