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BACKGROUND:The human immunoglobulin heavy‐chain (IGH) locus at chromosome 14q32 is frequently involved in different translocations of non‐Hodgkin lymphoma (NHL), and the detection of any breakage involving the IGH locus should identify a B‐cell NHL. The split‐signal IGH fluorescence in situ hybridization‐chromogenic in situ hybridization (FISH‐CISH) DNA probe is a mixture of 2 fluorochrome‐labeled...
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