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BACKGROUNDNew technologies, often with limited evidence to support their effectiveness, frequently diffuse into clinical practice and increase the costs of cancer care. The authors studied whether physician peer exposure was associated with the subsequent adoption of a new approach to adjuvant radiotherapy (brachytherapy) for the treatment of women with early‐stage breast cancer.
METHODSA retrospective...
BACKGROUNDPatient gender plays a significant role in patient‐physician communication, patients’ understanding of illness, and the aggressiveness of end‐of‐life (EoL) care. However, little is known about the extent to which gender differences in the effects of EoL discussions on EoL care contribute to gender differences in EoL care. The current study was aimed at determining whether gender differences...
BACKGROUNDPatient navigation (PN) may improve cancer care by identifying and removing patient‐reported barriers to care. In 2012, the American College of Surgeons Commission on Cancer (CoC) announced that health care facilities seeking CoC accreditation must have PN processes in place by January 1, 2015. Given these unfunded mandates, hospitals are looking for cost‐effective ways to implement PN....
BACKGROUNDThe impact of postoperative complications on the long‐term outcomes of patients undergoing surgery for cancer is unclear. The objective of the current study was to define the incidence of complications among patients undergoing surgery for intrahepatic cholangiocarcinoma (ICC) and identify the association between morbidity and long‐term outcomes.
METHODSA total of 583 patients undergoing...
BACKGROUNDThe objective of this study was to examine associations of symptoms with physical and mental health‐related quality of life (HRQOL) in patients with colorectal cancer (CRC) and in patients with lung cancer.
METHODSPatients with newly diagnosed CRC (n = 3040) or lung cancer (n = 2297) who were participating in the Cancer Care Outcomes Research and Surveillance Consortium study completed...
BACKGROUNDBiomarkers are routinely used to predict responses to systemic therapies, but their utility for predicting responses to local therapy for breast cancer is not known. This study determined whether biomarkers could predict responses to breast‐conserving therapy (BCT) and mastectomy.
METHODSA review of the Surveillance, Epidemiology, and End Results database identified women diagnosed with...
Despite the remarkable progress made in some leukemias such as CML and CLL, cytotoxic treatment for AML remains essentially unchanged over the last 4 decades. Several lines of evidence, including the graft versus leukemia effect associated with allogeneic hematopoietic stem cell transplantation (HSCT), suggest that immunotherapy is an active modality in AML. Given the lack of progress for chemotherapy...
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