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BACKGROUND
The purpose of this study was to examine variations in delivery of several breast cancer processes of care that are correlated with lower mortality and disease recurrence, and to determine the extent to which hospital volume explains this variation.
METHODS
Women who were diagnosed with stage I‐III unilateral breast cancer between 2007 and 2011 were identified within the National Cancer...
BACKGROUND
The outcomes of patients with unresected anaplastic thyroid carcinoma (ATC) from the National Cancer Data Base (NCDB) were assessed, and potential correlations were explored between radiation therapy (RT) dose and overall survival (OS).
METHODS
The study cohort was comprised of patients who underwent either no surgery or grossly incomplete resection. Correlates of OS were explored using...
BACKGROUND
Single‐modality radiotherapy is considered a standard‐of‐care option for certain stage III, T1‐2N1 head and neck squamous cell carcinomas (HNSCCs). The role of concomitant chemoradiation is not well established because there have been no studies comparing chemoradiation with radiation alone in this population.
METHODS
This study analyzed patients in the National Cancer Data Base with...
BACKGROUND
The current study was conducted to determine the effect of postoperative radiotherapy (PORT) on overall survival in patients with surgically managed pT3‐T4aN0 laryngeal squamous cell carcinoma (SCC).
METHODS
A review of the National Cancer Data Base from 2004 through 2013 was performed. Patients with surgically managed pT3‐4aN0 laryngeal SCC with negative surgical margins were included...
BACKGROUND
Adherence to evidence‐based treatment guidelines has been proposed as a measure of cancer care quality. The objective of this study was to determine the rate and predictors of care that does not adhere to National Comprehensive Cancer Network guidelines regarding commencing postoperative radiation therapy (PORT) within 6 weeks of surgery for patients with head and neck squamous cell carcinoma...
BACKGROUND
Concurrent chemoradiation (CCRT) and upfront surgery followed by adjuvant therapy both are recommended treatment options for patients with advanced stage squamous cell carcinoma (SCC) of the tonsil. To the authors' knowledge, the question of whether surgical‐based treatments can achieve better survival compared with CCRT has never been compared in a clinical trial. The authors analyzed...
BACKGROUND
The treatment of head and neck cancers is complex and associated with significant morbidity, requiring multidisciplinary care and physician expertise. Thus, facility characteristics, such as clinical volume and academic status, may influence outcomes.
METHODS
The current study included 46,567 patients taken from the National Cancer Data Base who were diagnosed with locally advanced invasive...
BACKGROUND
There is increasing evidence that primary tumor ablation can improve survival for some cancer patients with distant metastases. This may be particularly applicable to head and neck squamous cell carcinoma (HNSCC) because of its tropism for locoregional progression.
METHODS
This study included patients with metastatic HNSCC undergoing systemic therapy identified in the National Cancer...
BACKGROUND
The objective of this study was to determine the effects of National Comprehensive Cancer Network (NCCN) guideline–adherent initiation of postoperative radiation therapy (PORT) and different time‐to‐PORT intervals on the overall survival (OS) of patients with head and neck squamous cell carcinoma (HNSCC).
METHODS
The National Cancer Data Base was reviewed for the period of 2006‐2014,...
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