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BACKGROUNDThe delivery of effective treatment for pediatric solid tumors poses a particular challenge to centers in middle‐income countries (MICs) that already are vigorously addressing pediatric cancer. The objective of this study was to improve the current understanding of barriers to effective treatment of pediatric solid tumors in MICs.
METHODSAn ecologic model centered on pediatric sarcoma and...
BACKGROUNDAdult survivors of childhood cancer are at risk for suicide ideation, although longitudinal patterns and rates of recurrent suicide ideation are unknown. This study investigated the prevalence of late report (ie, after initial assessment) and recurrent suicide ideation in adult survivors of childhood cancer, identified predictors of suicide ideation, and examined associations among suicide...
BACKGROUNDLittle is known about infections among adult survivors of childhood cancer. The authors report the occurrence of infections and risk factors for infections in a large cohort of survivors of childhood cancer.
METHODSThe Childhood Cancer Survivor Study cohort was used to compare incidence rates of infections among 12,360 5‐year survivors of childhood cancer with the rates of 4023 siblings...
BACKGROUNDTo evaluate whether progress continues in identifying more effective treatments for children and adolescents with cancer, the authors examined both overall and disease‐specific childhood cancer mortality rates for the United States, focusing on data from 2000 to 2010.
METHODSAge‐adjusted US mortality trends from 1975 to 2010 were estimated using joinpoint regression analysis. Analyses of...
BACKGROUNDThe Childhood Cancer Research Network (CCRN) was established within the Children's Oncology Group (COG) in July 2008 to provide a centralized pediatric cancer research registry for investigators conducting approved etiologic and survivorship studies. The authors conducted an ecological analysis to characterize CCRN catchment at >200 COG institutions by demographic characteristics, diagnosis,...
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