The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
There is a considerable body of evidence about the adverse effects of cancer and cancer treatments on employment, work ability, work performance, and work satisfaction among cancer survivors. There is also a growing consensus that cancer survivorship research needs to address the large variety of short‐term and long‐term work‐related problems and that programs to support return to work and employment...
Cancer rehabilitation is a rapidly emerging and evolving medical field in both Europe and the United States, in large part because of increases in the number of cancer survivors. Although few argue with the need to restore function and quality of life to patients affected by cancer and its treatments, differences exist between European countries with regard to the funding, accessibility, and even...
The growing population of cancer survivors worldwide and the growing epidemics of obesity and physical inactivity have brought increased attention to the role that interventions to promote exercise and a healthy body weight may play in mitigating the chronic and late effects of cancer. In this light, the authors describe the similarities and differences in research and clinical priorities related...
The growing number of cancer survivors worldwide has led to of the emergence of diverse survivorship movements in the United States and Europe. Understanding the evolution of cancer survivorship within the context of different political and health care systems is important for identifying the future steps that need to be taken and collaborations needed to promote research among and enhance the care...
According to the recent worldwide estimation by the GLOBOCAN project, in total, 12.7 million new cancer cases and 7.6 million cancer deaths occurred in 2008. The worldwide number of cancer survivors within 5 years of diagnosis has been estimated at be almost 28.8 million. Informal caregivers, such as family members and close friends, provide essential support to cancer patients. The authors of this...
The multiple symptoms arising from cancer and its treatment impose significant distress for patients. However, in clinical research, there is no agreed‐upon way of assessing and presenting the effects of treatment on multiple symptoms, as either individual scores or a composite score. The ASCPRO (Assessing the Symptoms of Cancer Using Patient‐Reported Outcomes) Multisymptom Task Force was established...
BACKGROUND:Upper gastrointestinal adenocarcinomas (UGCs) respond poorly to current chemotherapeutic regimes. The authors and others have previously reported frequent Aurora kinase A (AURKA) gene amplification and mRNA and protein overexpression in UGCs. The objective of the current study was to determine the therapeutic potential of alisertib (MLN8237) alone and in combination with docetaxel in UGCs...
BACKGROUND:Although rural residents are more likely to be diagnosed with more advanced cancers and to die of cancer, little is known about rural‐urban disparities in self‐reported health among survivors.
METHODS:The authors identified adults who had a self‐reported history of cancer from the National Health Interview Survey (2006‐2010). Rural‐urban residence was defined using US Census definitions...
BACKGROUND:The National Lung Screening Trial (NLST) research team reported reduced lung cancer mortality among current and former smokers with a minimum 30 pack‐year history who were screened with spiral computed tomography scans compared with chest x‐rays. The objectives of the current study were to examine, at 1‐year follow‐up: 1) risk perceptions of lung cancer and smoking‐related diseases and...
BACKGROUND:Cancer patients and their oncologists often report differing perceptions of consultation discussions and discordant expectations regarding treatment outcomes. CONNECT, a computer‐based communication aid, was developed to improve communication between patients and oncologists.
METHODS:CONNECT includes assessment of patient values, goals, and communication preferences; patient communication...
BACKGROUND:Reliable predictive biomarkers are required to address the challenge of disease recurrence after thyroid cancer surgery. For this study, the authors assessed the association of cellular‐based and serum‐based immunologic mediators with thyroid cancer recurrence.
METHODS:Leukocyte subset counts and immune regulatory cytokine levels were determined in peripheral blood samples using multiparameter...
BACKGROUND:Routine screening for distress is internationally recommended as a necessary standard for good cancer care, given its high prevalence and negative consequences on quality of life. The objective of the current study was to contribute to the Italian validation of the Distress Thermometer (DT) to determine whether the single item DT compared favorably with referent criterion measures.
METHODS:In...
BACKGROUND:In postmarketing surveillance, the US Food and Drug Administration has reported the development of lung masses, thyroid cancer, and skin cancer after amiodarone therapy.
METHODS:Using the Taiwan National Health Insurance Research database, the authors conducted a population‐based cohort study. Patients who were treated with amiodarone between 1997 and 2008 were enrolled. Those with antecedent...
BACKGROUND:There is no validated system to identify prognostically distinct cohorts of women with uterine leiomyosarcoma (ULMS). By using an independent, pooled, multi‐institutional, international patient cohort, the authors validated a recently proposed ULMS nomogram.
METHODS:The ULMS nomogram incorporated 7 clinical characteristics (age, tumor size, tumor grade, cervical involvement, locoregional...
BACKGROUND:More women of fertile age are long‐term survivors of cancer. However, population‐based data on birth rates of female cancer survivors are rare.
METHODS:A total of 42,691 women ≤ 45 years with a history of cancer were identified from the Swedish Multi‐Generation Register and the Swedish Cancer Register, for whom relative birth rates were calculated as compared to the background population,...
BACKGROUND:Cancer registries use algorithms to process cause of death (COD) data from death certificates, but uncertainties remain regarding the accuracy and utility of those data in calculating cancer‐specific survival (CSS). Because it is impractical to reconfirm the COD through meticulous review of the primary medical records, the observed cancer deaths could be compared with the number of attributed...
BACKGROUNDThis study sought to develop a predictive model for 30‐day mortality in hospitalized cancer patients, by using admission information available through the electronic medical record.
METHODSObservational cohort study of 3062 patients admitted to the oncology service from August 1, 2008, to July 31, 2009. Matched numbers of patients were in the derivation and validation cohorts (1531 patients)...
BACKGROUNDCancer treatment accounts for approximately 5% of national health expenditures. However, no state‐level estimates of cancer treatment costs have been published.
METHODSIn analyses of data from the Medical Expenditure Panel Survey, the National Nursing Home Survey, the US Census Bureau, the Current Population Survey, and the Centers for Medicare & Medicaid Services, this study used regression...
BACKGROUNDProlonged, intensive treatment regimens often disrupt families of children with cancer. Siblings are at increased risk for distress, but factors underlying this risk have received limited empirical attention. In this study, the authors examined associations between the family context and sibling distress.
METHODSSiblings of children with cancer (ages 8‐18 years; N = 209) and parents (186...
BACKGROUNDBecause anaplastic thyroid cancer is a rare malignancy with a high mortality rate, the benefit of multimodality treatment was evaluated.
METHODSOverall survival was determined in the 2742 patients captured by the National Cancer Database who were diagnosed with anaplastic thyroid cancer between 1998 and 2008. Kaplan‐Meier analysis and then Cox proportional hazard regression was performed,...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.