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Background
Despite the significant societal burden of human papillomavirus (HPV)–associated cancers, clinical screening interventions for HPV‐associated noncervical cancers are not available. Blood‐based biomarkers may help close this gap in care.
Methods
Five databases were searched, 5687 articles were identified, and 3631 unique candidate titles and abstracts were independently reviewed by 2...
Background
Risk of recurrence among patients with oropharyngeal cancer (OPC) who survive 5 years is low. The goal of this study was to assess long‐term survival of patients with OPC alive without recurrence 5 years after diagnosis.
Methods
This study included newly diagnosed patients with OPC, who had been treated with radiation and were alive without recurrence 5 years after diagnosis. Overall...
BACKGROUND
Patients with human papillomavirus (HPV)‐driven oropharyngeal cancer (OPC) experience better survival than those with HPV‐negative OPC. It is unclear whether this benefit varies by demographic characteristics and serologic response.
METHODS
Records from 1411 patients with OPC who had HPV serology data were analyzed. HPV status was based on HPV type 16 (HPV16) E6 serology. Participants...
Background
Induction chemotherapy (IC) has been associated with a decreased risk of distant metastasis in locally advanced head and neck squamous cell carcinoma. However, its role in the treatment of oropharyngeal squamous cell carcinoma (OPSCC) is not well established.
Methods
The outcomes of patients with OPSCC treated with IC followed by concurrent chemoradiation (CRT) were compared with the...
Background
The oncologic outcomes of surgery alone for patients with American Joint Committee on Cancer 7th edition (AJCC 7th) pN2a and pN2b human papillomavirus–associated oropharynx squamous cell carcinoma (HPV+OPSCC) are not clear.
Methods
The authors performed a 12‐institution retrospective study of 344 consecutive patients with HPV+OPSCC (AJCC 7th pT0‐3 N3 M0) treated with surgery alone with...
Background
This study was conducted to identify clinicodemographic risk factors for xerostomia among long‐term oropharyngeal cancer (OPC) survivors.
Methods
This cross‐sectional study included 906 disease‐free, adult OPC survivors with a median survival duration at the time of survey of 6 years (range, 1‐16 years); self‐reported xerostomia scores were available for 877 participants. Study participants...
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