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BACKGROUND
The objective of the current study was to examine how modifiable factors such as satisfaction with cancer care and self‐efficacy impact health‐related quality of life (HRQOL) among Latino cancer survivors.
METHODS
Latinos previously diagnosed with breast, prostate, or colorectal cancer (N = 288) completed questionnaires (Patient Satisfaction with Cancer Care Scale, Stanford Chronic Disease...
BACKGROUND
Racial disparities in prostate cancer survival (PCS) narrowed during the prostate‐specific antigen (PSA) era, suggesting that screening may induce more equitable outcomes. However, the effects of lead time and overdiagnosis can inflate survival even without real screening benefit.
METHODS
A simulation model of PCS in the early PSA era (1991‐2000) was created. The modeled survival started...
BACKGROUND
Allogeneic hematopoietic stem cell transplantation (allo‐HCT) remains the only potentially curative treatment option for relapsed follicular lymphoma (FL), yet questions remain about the optimal timing. This study analyzed long‐term outcomes and associated factors among recipients of allo‐HCT with FL.
METHODS
Patients with relapsed FL who underwent allo‐HCT from 2001 to 2011 with a human...
BACKGROUND
Inotuzumab ozogamicin (InO) has demonstrated efficacy and tolerability in patients aged 18 to 78 years with relapsed/refractory acute lymphoblastic leukemia (ALL) in the INO‐VATE trial. This subset analysis compared the efficacy and safety of InO in younger and older patients.
METHODS
Intent‐to‐treat analyses of morphologic responses and overall survival (OS) included 326 randomized...
BACKGROUND
Anaplastic thyroid cancer (ATC) is the rarest type of thyroid cancer and has the lowest overall survival. To the authors' knowledge, the impact of socioeconomic status and race/ethnicity has not yet been described.
METHODS
Data regarding 719 patients diagnosed with their first primary malignant ATC from January 1, 1998 to December 31, 2011 in the Surveillance, Epidemiology, and End Results...
BACKGROUND
Molecular tests have clinical utility for thyroid nodules with indeterminate fine‐needle aspiration (FNA) cytology, although their performance requires further improvement. This study evaluated the analytical performance of the newly created ThyroSeq v3 test.
METHODS
ThyroSeq v3 is a DNA‐ and RNA‐based next‐generation sequencing assay that analyzes 112 genes for a variety of genetic...
BACKGROUND
The assessment of pancreatic ductal adenocarcinoma (PDAC) response to therapy remains challenging. The objective of this study was to investigate whether changes in the tumor/parenchyma interface are associated with response.
METHODS
Computed tomography (CT) scans before and after therapy were reviewed in 4 cohorts: cohort 1 (99 patients with stage I/II PDAC who received neoadjuvant...
BACKGROUND
Although outcomes for patients with squamous cell carcinoma of the anus (SCCA) have improved, the gains in benefit may not be shared uniformly among patients of disparate socioeconomic status. In the current study, the authors investigated whether area‐based median household income (MHI) is predictive of survival among patients with SCCA.
METHODS
Patients diagnosed with SCCA from 2004...
BACKGROUND
Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider factors on testing are scarce.
METHODS
The authors used a statewide, multipayer,...
Chronic myeloid leukemia (CML) has evolved into a chronic disease that is managed with tyrosine kinase inhibitor therapy. Now that long‐term survival has been achieved in patients with CML, the focus of treatment has shifted to dose optimization, with the goal of maintaining response while improving quality of life. In this review, the authors discuss optimizing the dose of the second‐generation tyrosine...
Colorectal cancer (CRC) remains the third most common malignancy and the second‐leading cause of cancer‐related deaths in the United States. Large multi‐omic databases, such as The Cancer Genome Atlas and the International Colorectal Cancer Subtyping Consortium, have identified distinct molecular subtypes related to anatomy. The identification of genomic alterations in CRC is now critical because...
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