Clin Microbiol Infect 2011; 17: 1441–1444
Abstract
Fifty‐six isolates of serotype 1 were identified during a 20‐year prospective study (1989–2008), including all children with culture‐proven invasive pneumococcal disease (IPD) admitted to a children’s hospital in Barcelona. Forty‐eight of them (85.7%) were in children aged >2 years. Complicated pneumonia (n = 28) and non‐complicated pneumonia (n = 20) were the main clinical presentations. The frequency of serotype 1 IPD increased from 1999–2003 to 2004–2008: 1.2 to 4.4 episodes/100 000 children (p <0.001). The ST306 clone were identified in 70.4% of isolates. As IPD caused by serotype 1 is mainly detected in older children, a vaccination programme for children >2 years should be considered.