A fascinating class of soft materials are supramolecular gels which have attracted significant attention in recent years. They are composed of small molecule gelators that assemble into supramolecular network structures. Some gel materials are able to respond to various stimuli making them attractive drug delivery vehicles and as matrices for tissue regeneration. Peptide‐based gel materials are particularly attractive as they possess numerous advantages including biocompatibility and biodegradability. Stimuli‐responsive peptides that alter properties as a function of pH, redox, temperature, and enzymes offer the potential to create materials with tunable characteristics. Herein, the stimuli‐responsive properties (pH, redox, temperature, and enzyme responsive properties), as well as the biocompatible/‐degradable nature of the peptide gelators are highlighted, for more details, see the Minireview by H.‐B. Kraatz and N. Falcone on page 14316 ff.