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Fluorescence signals obtained from microarrays for single nucleotide polymorphism genotyping show systematic strong variations in the levels for single nucleotide polymorphisms and arrays as well as genotypes. Linear models that take all three effects into account fit very well. Once the model parameters have been estimated for a set of reference arrays, they can be used to calibrate new arrays in...
This review covers the application of Genetic Algorithms (GAs) in Chemometrics. The first applications of GAs in chemistry date back to the 1970s, and in the last decades, they have been more and more frequently used to solve different kinds of problems, for example, when the objective functions do not possess properties such as continuity, differentiability, and so on. These algorithms maintain and...
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