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Background
Sialic acid‐binding immunoglobulin‐like lectin (Siglec)‐8 is expressed on mast cells and eosinophils, but information about Siglec‐8 expression and function in the lung is limited. A humanized antibody, AK002, targeting Siglec‐8 is undergoing development for treatment of diseases associated with mast cell and eosinophil‐driven inflammation.
Objective
To characterize Siglec‐8 expression...
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