We examined the relationship between calling, job‐search clarity, and job‐search intensity in a cross‐sectional study of Italian unemployed job seekers (N = 315). Structural equation modeling with observed variables and latent moderated structural equation models were adopted to test whether optimism, self‐esteem, and perseverance moderate the relation between calling, job‐search clarity, and job‐search intensity. Perceiving a calling was positively related with job‐search clarity and intensity, and these relations were stronger in individuals with lower levels of optimism, self‐esteem, and perseverance. This study suggests that perceiving a calling is an important personal resource that is related to a clearer job‐search goal and to more intense job‐search activities and can support job seekers in personal adverse conditions. These results suggest integrating job‐search behaviors in the work‐as‐calling theory and that incorporating the construct of calling into career counselors' practices may increase the efficacy of job‐search activities.