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Chromatographic separation of the AcOEt extract of the fermented cultures of the deep‐sea‐derived fungus Graphostroma sp. resulted in the isolation of 11 new chained polyketides, namely graphostromols A–K (1–11). The structures of the new compounds were established by the extensive analyses of their NMR and HR‐ESI‐MS data. The absolute configuration at C‐11 in 1 was determined on the basis of the...
Front Cover. With the advancement in submersible technology, more and more marine microorganisms have been isolated from deep‐sea environments. However, as the most extreme and dynamic environments of the world, the deep‐sea hydrothermal vents are still poorly investigated. Graphostroma sp. MCCC 3 A00421 was isolated from hydrothermal sulfide deposits of the Atlantic Ocean at the depth of −2721 m...
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