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Phytochemical study on the fruit of Cornus officinalis Sieb. et Zucc. yielded two new iridoid glucosides, named cornusglucoside A (1) and cornusglucoside B (2). The structures of 1 and 2 were elucidated via comprehensive NMR and HR‐ESI‐MS data analysis. Additionally, their inhibitory effects on IL‐6‐induced STAT3 activation were assessed.
Cover Picture. Cornus officinalis Siebold & Zucc. in the Cornaceae family is a deciduous tree growing in most areas of China, including Shaanxi, Henan and Zhejiang. The fruit of C. officinalis, also known as Corni Fructus, is used as a well‐known Chinese medicine to treat a number of diseases, including diabetes, nephropathy and hepatopathy. To further enhance the search for structurally diverse...
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