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Enoyl acyl carrier protein reductase (InhA) is a promising target for the development of antituberculosis drugs. The InhA‐bound conformation of an indole‐5‐amide inhibitor (Genz 10850) (PDB code: IP44) was used to build a pharmacophore model by LigandScout. This model was then successfully used to identify the bioactive conformation and align 40 structurally diverse arylcarboxamide derivatives. Comparative...
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