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Since the year 1993, when 5‐HT7 receptor (5‐HT7R) was discovered, there is no selective 5‐HT7R ligand introduced to the pharmaceutical market. One out of the main reasons disqualifying the 5‐HT7R ligands is weak drugability properties, including metabolic instability or low permeability. This study is focused on the search of a lead compound by “drug‐likeness” estimation of the first series of selective...
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