This chapter presents the diagnosis and treatment for corneal dystrophy that mostly occurs in Cavalier King Charles Spaniel, Siberian Husky, Beagle, and Shetland Sheepdog. Corneal dystrophy describes a group of corneal disorders in which cholesterol, phospholipids, and free fatty acids accumulate within the cornea(s). This disorder is bilateral in presentation and is not associated with any preexisting or concurrent corneal or ocular inflammation. Multiple patterns of corneal dystrophy include axial or peripheral, ovoid to circular lesions. Corneal dystrophy is diagnosed based on clinical findings. Treatment is frequently unnecessary and corticosteroid‐based anti‐inflammatory medications may exacerbate changes. Keratectomy may be indicated in rare cases of secondary ulceration and/or mineralization associated with epithelial discontinuity and discomfort.