This chapter presents the diagnosis and treatment for conjunctival squamous cell carcinoma (SCC), which occurs in the Pug and the English Bulldog. Hereditary factors, exposure to UV sunlight and/or chronic inflammation may contribute to the development of conjunctival and/or third eyelid (TEL) SCC. Clinically, SCC presents as irregular, pink‐colored proliferative to erosive lesions. The diagnosis of SCC is made by histopathology following incisional or excisional biopsy, with SCC frequently appearing clinically similar to chronic corneal inflammation/granulation. Systemic health should be evaluated via local lymph node aspiration, three‐view radiography, and complete blood count (CBC)/chemistry analysis. Focal swelling is common postoperatively. Postoperative care comprises topical and or systemic anti‐inflammatory and/or antimicrobial therapy as appropriate and the use of an Elizabethan collar to prevent self‐trauma.