This chapter presents an overview of prolepses of the lacrimal gland of the third eyelid (“cherry eye”). Glandular prolapse arises as a result of defective connective tissue development and consequent glandular laxity in predisposed breeds. Third eyelid gland prolapse typically affects young animals. Associated symptoms may include conjunctivitis, ocular discharge, and/or decreased lacrimal function as well as secondary ulcerative keratitis. Severe secondary inflammation and or bacterial infection may develop, particularly in cases of chronic glandular prolapse. The ideal treatment represents surgical repositioning of prolapsed tissue. Several techniques for repair have been described, with the “Morgan pocket” technique being most generally appropriate. Postoperative care comprises routine systemic antimicrobial, anti‐inflammatory, and analgesic care. An Elizabethan collar should be placed in order to prevent self‐trauma and corneal health should be frequently monitored until third eyelid healing is complete.