This chapter shows the possibilities of electrochemical immunosensing for food analysis. In the chapter, examples of electrochemical immunosensors for different targets, including also pharmaceuticals or special analytes such as those related to food allergies, are given. A very important group of biosensors in the food field is devoted to food allergy or intolerance, an abnormal (immunological or not) response due to sensitivity to a food component. The chapter considers important issues referring to immunoreagents, antibodies, and antigens. The covalent attachment is widely used in immunosensors, being the most common this is based on the EDC/NHS chemistry, the chemistry of carbodiimide. One of the challenges of immunosensors is their automation, especially relevant in food quality, when high number of samples, or continuous food processes are involved. Electrochemical immunosensors are very adequate devices for food analysis, since the enormous selectivity of the antibody–antigen system is combined to highly sensitive detection techniques.