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Opioids are important endogenous ligands that exist in both invertebrates and vertebrates and signal by activation of opioid receptors to produce analgesia and reward or pleasure. The μ‐opioid receptor is the best known of the opioid receptors and mediates the acute analgesic effects of opiates, while the δ‐opioid receptor (DOR) has been less well studied and has been linked to effects that follow...
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