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Closure of the ductus arteriosus at birth is known to be related to the physiological rise in blood oxygen tension. Two main schemes have been proposed to explain the peculiar contraction of the ductus to oxygen, and their function is based on distinct sensor‐effector complexes. Specifically, these schemes comprise a cytochrome P450 monooxygenase‐endothelin complex or, alternatively, a mitochondrial...
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