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The regenerating tail blastema of lizards appears immunesuppressed, and the distribution of hyaluronate, a possible agent of immunesuppression, is evaluated. Transcriptome data show upregulation of genes stimulating hyaluronate production in the tail and limb blastemas. The distribution of hyaluronate in the tail and limb blastemas has been studied using alcian blue at pH 2.5 and 1.0 and by immunohistochemistry...
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