Effects of a group health promotion program on well‐being and absenteeism of employees and skilled workers were tested. The objectives of the program are systematic self‐monitoring and reflection on everyday life health behavior as well as the promotion of health‐ and development‐related cognitions and well‐being. Randomised group designs were employed to evaluate the program's effects on well‐being, psychosomatic complaints, personal regulation of own development, and absenteeism. Program effects were confirmed with reference to these outcome measures administered at the end of the 8‐week treatment and at 2‐month follow‐up in samples of 56 public employees (Study 1) and 39 skilled workers (Study 2). Results demonstrate the effectiveness and usability of the SySeRe program as an economical individual‐level health promotion intervention in occupational health psychology with large effect sizes in psychometric measures of well‐being and in the reduction of employee sick leave as well.