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Purpose
To assess the potential role of amphiregulin as messenger molecule in ocular axial elongation.
Methods
The experimental study included guinea pigs (total n = 78) (age: 3–4 weeks) which underwent bilateral lens‐induced myopization and received 15 days later three intraocular injections in weekly intervals of amphiregulin antibody (doses:5 μg, 10 μg, 20 μg) into their right eyes, and three...
Purpose
To study the genetic aetiology and phenotypes of retinal degeneration (RD) in Finnish children born during 1993–2009.
Methods
Children with retinal degeneration (N = 68) were investigated during 2012–2014 with a targeted gene analysis or a next‐generation sequencing (NGS) based gene panel. Also, a full clinical ophthalmological examination was performed.
Results
The cohort covered 44%...
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