The Dutch Ultra‐Thin DSAEK study is a multicenter randomized controlled study comparing the effectiveness and cost‐effectiveness of precut ultra‐thin (<100 m) DSAEK with standard thickness DSAEK. Fifty‐eight adult patients with Fuchs endothelial dystrophy and no other visual limiting comorbidities were randomized to either ultra‐thin or standard DSAEK in four tertiary medical centers in The Netherlands. Preliminary (6 months follow‐up) outcomes, including: ETDRS best corrected visual acuity, refractive and topographic astigmatism, endothelial cell density, contrast sensitivity, straylight, complication profile, quality of life and vision related quality of life will be presented.