Purpose Posterior uveitis comprises a heterogenous group of diseases with inflammatory alterations of the posterior fundus and is a common cause of visual impairment and blindness. The goal of this study is to evaluate the diagnostic value of wide‐field‐fundusautofluorescence (FAF) of patients with non‐infectious posterior uveitis and chorioretinal alterations.
Methods 73 eyes from 51 patients were included. Best‐corrected visual acuity, wide‐field color and FAF images achieved by a wide‐field SLO (Optomap P200Tx, Optos PLC, Dunfermline, Fife, Scotland, UK) and a full ophthalmological examination were obtained from each patient. A systematic analysis of chorioretinal alterations detected with FAF and color images was conducted followed by the evaluation of the diagnostic information of wide‐field FAF compared to the clinical finding and wide‐field color images respectively.
Results 52 of 73 included cases showed peripheral alterations. In 32 cases, wide‐field FAF images revealed a greater number and more extended chorioretinal alterations than corresponding wide‐field color images of the posterior fundus.
Conclusion In this study, wide‐field FAF images showed more chorioretinal alterations than seen in funduscopy or in color SLO images. Therefore, wide‐field FAF images offer important additional information in detection and documentation of peripheral and central chorioretinal alterations.