Purpose A goal of the present paper was an assessment of usefulness of latency of P100 wave in describing few pathological disorders in children. The study group comprised 268 children, including 68 with cytomegaly (CM), 59 with myelomeningocele (MM) , 69 with purulent meningitis(PM) and 73 with Down’s syndrome (DS). The control group consisted of 592 healthy children.
Methods Registrations were performed using Visual Evoked Potentials for each patient, stored on data bank and evaluated automatically with manual correction. Collected values of P100 wave’s latency were analyzed using typical statistical tools (t‐test contained in STATISTICA‐data analysis software system. StatSoft, Inc. 2011, version 10. www.statsoft.com).
Results The comparison performed in regard to the group‐mean latencies of the analyzed P100 wave between the control group and the four studied groups revealed statistically significant differences (p<0.0001). There were also statistically significant differences in the mean P100 latency between DS group and CM and PM groups (p<0.0001). Evaluation of the mean latencies in three groups (CM, MM and PM) did not reveal statistically significant differences (p>0.05).
Conclusion The results show the differences in mean latency of P100 wave between normal subjects and children with pathological disorders. In children with Down’s syndrome observed abnormalities were smaller than in other 3 groups.