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Pamamycine sind Makrodiolide polyketider Herkunft, die antibakteriell wirken. Es wurde postuliert, dass ihre Biosynthese Succinat als Baustein verwendet. Jedoch war der Mechanismus des Succinat‐Einbaus in ein Polyketid unklar. Hier berichten wir über die Identifizierung eines Pamamycin‐Biosynthese‐Genclusters durch Vergleich der Genome zweier Pamamycin‐produzierender Stämme. Dieses einzigartige Cluster...
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