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Künstliche Viren Y. Chao und R. Ni berichten in ihrem Forschungsartikel auf S. 3606 über die Bildung von künstlichen sphärischen Peptid‐DNA‐Viren durch die hierarchische Zusammenlagerung eines Peptids mit DNA. Die Nanostruktur zerfällt sequenziell bei pH 5.
Protein subunits of a low aspect ratio (width over length) with stimuli‐responsiveness are hallmark building blocks of spherical viruses. The interaction of these repeating subunits enables hierarchical assembly for genome packaging and sequential disassembly for optimal genome release. Here, we mimicked these features and constructed a functional spherical artificial virus. The rationally designed...
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