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The impact of the use of loop diuretics to prevent cumulative fluid balance in non‐oliguric patients is uncertain. This is a retrospective study to estimate the association of time‐averaging loop diuretic exposure in a large population of non‐cardiac, critically ill patients with a positive fluid balance (> 5% of body weight). The exposure was loop diuretic and the main outcomes were 28‐day mortality,...
The epidemiology of peri‐operative acute kidney injury varies depending on the definition, type of surgery and acute and chronic comorbidities. Haemodynamic instability, disturbance of the microcirculation, endothelial dysfunction, inflammation and tubular cell injury are the main factors contributing to the pathogenesis. There are no specific therapies. The most effective strategies to protect renal...
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