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Background: Recent data suggest that the previously rising trend in childhood wheezing symptoms has plateaued in some regions. We sought to investigate sex‐specific trends in wheeze, asthma, allergic conditions, allergic sensitization and risk factors for wheeze.
Methods: We compared two population‐based cohorts of 7 to 8‐year olds from the same Swedish towns in 1996 and 2006 using parental expanded...
To cite this article: Contoli M, Bousquet J, Fabbri LM, Magnussen H, Rabe KF, Siafakas NM, Hamid Q, Kraft M. The small airways and distal lung compartment in asthma and COPD: a time for reappraisal. Allergy 2010; 65: 141–151.
AbstractThe involvement of small airways in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD) has been debated for a long time. However, a proper definition...
To cite this article: Anandan C, Nurmatov U, van Schayck OCP, Sheikh A. Is the prevalence of asthma declining? Systematic review of epidemiological studies. Allergy 2010; 65: 152–167.
AbstractAsthma prevalence has increased very considerably in recent decades such that it is now one of the commonest chronic disorders in the world. Recent evidence from epidemiological studies, however, suggests that...
To cite this article: Bunyavanich S, Soto‐Quiros ME, Avila L, Laskey D, Senter JM, Celedón JC. Risk factors for allergic rhinitis in Costa Rican children with asthma. Allergy 2010; 65; 256–263 DOI: 10.1111/j.1398‐9995.2009.02159.x.
AbstractBackground: Risk factors for allergic rhinitis (AR) in asthmatics are likely distinct from those for AR or asthma alone. We sought to identify clinical and environmental...
To cite this article: Reijmerink NE, Bottema RWB, Kerkhof M, Gerritsen J, Stelma FF, Thijs C, van Schayck CP, Smit HA, Brunekreef B, Koppelman GH, Postma DS. TLR‐related pathway analysis: novel gene–gene interactions in the development of asthma and atopy. Allergy 2010; 65: 199–207.
AbstractBackground: The toll‐like receptor (TLR)‐related pathway is important in host defence and may be crucial in...
To cite this article: Thunberg S, Gafvelin G, Nord M, Grönneberg R, Grunewald J, Eklund A, van Hage M. Allergen provocation increases TH2‐cytokines and FOXP3 expression in the asthmatic lung. Allergy 2010; 65: 311–318.
AbstractBackground: Allergic asthma is caused by allergen‐specific IgE and T‐helper cell (Th) type 2 responses towards airborne allergens. The objective of this study was to investigate...
To cite this article: Randriamanantany ZA, Annesi‐Maesano I, Moreau D, Raherison C, Charpin D, Kopferschmitt C, Lavaud F, Taytard A, De Blay F, Caillaud D. Alternaria sensitization and allergic rhinitis with or without asthma in the French Six Cities study. Allergy 2010; 65: 368–375.
AbstractBackground: Allergic sensitization to Alternaria has been related to asthma in various studies, but its association...
To cite this article: Hatzivlassiou M, Grainge C, Kehagia V, Lau L, Howarth PH. The allergen specificity of the late asthmatic reaction. Allergy 2010; 65: 355–358.
AbstractBackground: Allergen inhalation challenge in asthma may induce both early (EAR) and late (LAR) asthmatic reactions. The EAR is IgE and mast cell dependent. The mechanism of the LAR is less well defined and we have hypothesized...
To cite this article: Nair A, Vaidyanathan S, Clearie K, Williamson P, Meldrum K, Lipworth BJ. Steroid sparing effects of intranasal corticosteroids in asthma and allergic rhinitis. Allergy 2010; 65: 359–367.
AbstractBackground: Treating allergic rhinitis may have a downstream anti‐inflammatory effect on the lower airways. We conducted a dose ranging study in asthma and persistent allergic rhinitis...
To cite this article: Hasford J, Uricher J, Tauscher M, Bramlage P, Virchow JC. Persistence with asthma treatment is low in Germany especially for controller medication – a population based study of 483 051 patients. Allergy 2010; 65: 347–354.
AbstractBackground: The objective of the present analysis was to evaluate treatment patterns and persistence with treatment of an unselected patient population...
To cite this article: Ruotsalainen M, Piippo‐Savolainen E, Hyvärinen MK, Korppi M. Adulthood asthma after wheezing in infancy: a questionnaire study at 27 years of age. Allergy 2010; 65: 503–509.
AbstractBackground: Wheezing in early childhood is a heterogeneous condition, the long‐term prognosis varying from total recovery to chronic asthma. Though short‐term outcome has been actively studied,...
To cite this article: Pérez‐Ríos M, Ruano‐Ravina A, Etminan M, Takkouche B. A meta‐analysis on wood dust exposure and risk of asthma. Allergy 2010; 65: 467–473.
AbstractWork‐related asthma is the most common occupational respiratory disorder in the industrialized countries. It has been postulated that wood dust exposure may increase the risk of work‐related asthma. The objective of this study was...
To cite this article: Quirce S, Lemière C, de Blay F, del Pozo V, Gerth Van Wijk R, Maestrelli P, Pauli G, Pignatti P, Raulf‐Heimsoth M, Sastre J, Storaas T, Moscato G. Noninvasive methods for assessment of airway inflammation in occupational settings. Allergy 2010; 65: 445–458.
AbstractThe present document is a consensus statement reached by a panel of experts on noninvasive methods for assessment...
To cite this article: Agondi RC, Barros MT, Rizzo LV, Kalil J, Giavina‐Bianchi P. Allergic asthma in patients with common variable immunodeficiency. Allergy 2010; 65: 510–515.
AbstractBackground: Many patients with common variable immunodeficiency (CVID) have a clinical history suggestive of allergic respiratory disease. However, in such individuals, the prevalence of asthma and the role of atopy...
To cite this article: Mahut B, Trinquart L, Le Bourgeois M, Becquemin M‐H, Beydon N, Aubourg F, Jala M, Bidaud‐Chevalier B, Dinh‐Xuan A‐T, Randrianarivelo O, Denjean A, de Blic J, Delclaux C. Multicentre trial evaluating alveolar NO fraction as a marker of asthma control and severity. Allergy 2010; 65: 636–644.
AbstractBackground: Exhaled NO can be partitioned in its bronchial and alveolar sources,...
To cite this article: Oflu A, Soyer OU, Tuncer A, Sackesen C, Kalayci O. Eccrine sweat response in children with asthma. Allergy 2010; 65: 645–648.
AbstractBackground: Even though there is a general conviction among parents of asthmatic children and pediatricians that asthmatic children sweat more than healthy ones, this has not been formally tested.Aim: To determine sweating response and factors...
To cite this article: Bakolis I, Hooper R, Thompson RL, Shaheen SO. Dietary patterns and adult asthma: population‐based case–control study. Allergy 2010; 65: 606–615.
AbstractBackground: Epidemiological studies of diet and asthma have focused on relations with intakes of individual nutrients and foods and evidence has been conflicting. Few studies have examined associations with dietary patterns...
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