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Engineering of efficient and safe materials remains a challenge for cancer therapy. Here, the lipid droplet, an organelle in adipocytes, is demonstrated to be a controllable and biocompatible vehicle to deliver anticancer drugs. It is validated that isolated lipid droplets maintain their key physiological functions to interact with other organelles and augment the therapeutic effect of cancer photodynamic...
In article number 2100629, Liping Jiang, Jun‐Jie Zhu, Zhen Gu and co‐workers develop a lipid‐droplet‐based drug delivery system for cancer photodynamic therapy. The lipid droplet, which is derived from adipocytes, is leveraged to potentiate the anticancer efficacy of the lipid‐conjugated drug.
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