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As peripheral lymphocytes are typically excluded from the gastrointestinal lymph tissues, current parenteral vaccinations fail to simultaneously induce systemic and mucosal responses. To break the natural barrier, “immunoticket” capsules are developed and heralded, which are designed with positive charged shells and oily core to spatiotemporally deliver antigens and all‐trans retinoic acid (RA). After...
Typically, parenteral vaccinations hardly induce mucosal immune responses. To address this, in article number 1801067, Zhiguo Su, Guanghui Ma, and co‐workers develop oil‐in‐polymer capsules to co‐deliver antigens and retinoic acid, which function as an “immunoticket” to cultivate peripheral lymphocytes with gut‐homing receptors and hitchhike on the “express train” of the CCL25 concentration gradient...
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