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Immunogenic cell death (ICD) provides momentous theoretical principle for modern cancer immunotherapy. However, the currently available ICD inducers are still very limited and photosensitizer‐based ones can hardly induce sufficient ICD to achieve satisfactory cancer immunotherapy by themselves. Herein, an organic photosensitizer (named TPE‐DPA‐TCyP) with a twisted molecular structure, strong aggregation‐induced...
In article number 1904914, Dan Ding and co‐workers demonstrate that focused mitochondrial oxidative stress can massively evoke immunogenic cell death (ICD) in cancer immunotherapy, and that aggregation‐induced emission (AIE) is a desirable platform for developing advanced photosensitizer‐based ICD inducers.
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