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Nanomaterials (NMs) are widely used in commercial and medical products, such as cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal, inhalation, and ingestion has been shown to gain access to the systemic circulation, resulting in the accumulation of NMs in the liver. The unique organ structures and blood flow features facilitate the liver sequestration of NMs,...
Nanomedicine
The liver is the primary accumulation site for intravenously administered nanocarriers or incidental nanoparticles that gain access to the systemic circulation. Liver distribution and cellular uptake of nanoparticles by various liver cells could influence the therapeutic efficacy. Understanding nano–liver interactions is critical for the design of much safer and more effective nano‐theranostics...
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