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Integration of plasmonic nanostructures with fiber‐optics‐based neural probes enables label‐free detection of molecular fingerprints via surface‐enhanced Raman spectroscopy (SERS), and it represents a fascinating technological horizon to investigate brain function. However, developing neuroplasmonic probes that can interface with deep brain regions with minimal invasiveness while providing the sensitivity...
Neurochemical Detection
In article number 2200902, Di Zheng, Massimo De Vittorio, Ferruccio Pisanello, and co‐workers present a surface‐enhanced Raman scattering (SERS)‐active probe based on a tapered optical fiber decorated with sub‐10 nm‐gap gold nanoislands, which is designed for neurochemical detection. Through‐fiber measurements show the fabricated device can detect neurotransmitters down to...
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