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In article number 2004537, Xinhua Qu, Bing Yue, Wei‐En Yuan, and co‐workers design and construct a multilayered nerve guidance conduit loaded with melatonin and Fe3O4 magnetic nanoparticles by electrospinning. Sequential and sustainable release of bioactive agents provides a supportive microenvironment for nerve regeneration, showing great potential for the long‐term treatment of peripheral nerve...
Peripheral nerve injury is a common clinical problem bringing heavy burden to patients, due to its high incidence and unsatisfactory treatment. Nerve guidance conduit (NGC) is a promising scaffold for peripheral nerve repair, and bioactive agents are applied for great functional recovery. Melatonin (MLT) and Fe3O4 magnetic nanoparticles (Fe3O4‐MNPs) are proven to inhibit oxidative stress, inflammation,...
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